General Information

  • ID:  hor001143
  • Uniprot ID:  A0A7M7L8Y0
  • Protein name:  TWKSPDIVIRFa–FMRFa-like
  • Gene name:  100578542
  • Organism:  Apis mellifera (Honeybee)
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SVLTTLKTDGGLRIFKDAPNEF
  • Length:  22
  • Propeptide:  MSCLSSLYVLPFICNCVLVSSSVLTTLKTDGGLRIFKDAPNEFKDVPNEFEEALKRHSIDCHSDKRENPQGCSGSFFVRDERSDPDRGKERFYNGDGDRGSNRSPRTWKSPDIVIRFGRAGFKNLNREQKRGRNDLNFIRYGRGMQIYPDSVVTAICSNLLSNEDIQPYEARLLRFCNCLNNNDVDHRENLDFFEDRLGTKHD
  • Signal peptide:  MSCLSSLYVLPFICNCVLVSS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7L8Y0-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001143_AF2.pdbhor001143_ESM.pdb

Physical Information

Mass: 279752 Formula: C109H176N28O34
Absent amino acids: CHMQWY Common amino acids: LT
pI: 6.55 Basic residues: 3
Polar residues: 7 Hydrophobic residues: 8
Hydrophobicity: -18.64 Boman Index: -3465
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 88.64
Instability Index: 2197.27 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera